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Amakuru

Ubumenyi bukunzwe bwa siyansi yubumenyi bwamasaro

Amasaro ya magneti akoreshwa cyane mugupima ubudahangarwa bw'umubiri, gusuzuma molekile, kweza poroteyine, gutondekanya selile, no mubindi bice

Immunodiagnose: Isaro rya Immunomagnetic rigizwe nuduce twa magnetique nibikoresho bifite amatsinda akora. Intungamubiri za poroteyine (antigens cyangwa antibodies) zifatanije hamwe hamwe nitsinda ryimikorere yamasaro ya magneti, hanyuma immunoassay ikorwa hifashishijwe amashanyarazi ya magnetiki.

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Kwipimisha kwa molekuline (gukuramo aside nucleic): Amasaro ya nanoscale ya magnetique hamwe nitsinda ryubutaka rishobora adsorb acide nucleic irashobora gutandukanywa no kwamamazwa numurima wa rukuruzi, hanyuma ugahitamo kugirango ubone aside nucleic aside.

Isuku rya poroteyine: Umusaraba uhuza agarose uhujwe hamwe na poroteyine ya recombinant fusion proteine ​​A / G hejuru y’amasaro ya magneti, poroteyine yihariye ihuza ProteinA / G, amaherezo ikavamo kugira ngo ibone antibodi zisukuye.

Gusuzuma Immune no Gusuzuma Molecular:

Bumwe mu buryo bw'ingenzi bukoreshwa mu masaro ya magnetiki ni mu gusuzuma indwara, aho zabaye ibikoresho by'ingenzi mu kumenya indwara neza. Umwihariko udasanzwe wamasaro ya magnetique ukomoka kubushobozi bwabo bwo gufata no gutandukanya antigene cyangwa antibodies zihariye kuburugero rwabarwayi, byoroshya inzira yo gusuzuma. Muguhuza hamwe na protein ligands, nka antigene cyangwa antibodies, mumatsinda yimikorere yamasaro ya magneti, abashakashatsi barashobora gukora immunoassay neza kandi neza neza.Kwipimisha kwa molekuline, undi murima ushimishije, wungukirwa cyane no gukoresha amasaro ya magneti. Hamwe nubuhanga bwo gupima molekuline bumaze kumenyekana mumyaka yashize, amasaro ya magneti agira uruhare runini mugutandukanya no gukuramo aside nucleique nka ADN cyangwa RNA, mubushakashatsi bwibinyabuzima. Aya masaro akora nkinkunga ikomeye, yorohereza gufata no kweza neza molekile yagenewe. Ubu buryo buteye imbere bwatumye abahanga bagera ku isuzuma ryukuri kandi ryizewe, biganisha ku barwayi beza.

Kweza poroteyine no gutondekanya selile:

Amasaro ya Magnetique nayo asanga ikoreshwa cyane mugusukura poroteyine, inzira ikomeye mugutezimbere ibiyobyabwenge nubushakashatsi bwibinyabuzima. Muguhuza ligande yihariye kumasaro, abashakashatsi barashobora guhitamo no gukuramo poroteyine zigamije kwera no gutanga umusaruro. Ubu buryo bwo kweza bwihutisha cyane inzira yubushakashatsi muri rusange, butuma abahanga basesengura kandi bakiga poroteyine muburyo burambuye.Gutondekanya ingirabuzimafatizo, igice cyingenzi mubikorwa bitandukanye byubuvuzi nubushakashatsi, nubundi buryo bwungukirwa cyane namasaro. Aya masaro, afatanije na biomarkers cyangwa antibodies, byorohereza kwigunga no gutondekanya mubaturage batandukanye. Mugukoresha umurima wa magneti, abahanga barashobora gutondeka neza no gutandukanya ingirabuzimafatizo zishingiye kubiranga umubiri nibikorwa. Ubworoherane nukuri kwubu buhanga byashimangiye imbaraga zubushakashatsi mugusobanukirwa inzira zingirabuzimafatizo, nko gutera kanseri no kurwanya indwara.

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Igihe cyo kohereza: Jun-25-2023